The symptoms of reactive arthritis usually go away within 35 months. COVID-19 vaccines can cause mild side effects after the first or second dose, including: Pain, redness or swelling where the shot was given Fever Fatigue Headache Muscle pain Chills Joint pain Nausea and vomiting Swollen lymph nodes Feeling unwell Most side effects go away in a few days. Accessibility SBI Recommendations for the Management of Axillary Adenopathy in Patients with Recent COVID-19 Vaccination . Note: Content may be edited for style and length. It is created by eHealthMe based on reports of 401,887 people who have side effects when getting Pfizer BioNTech Covid Vaccine from the CDC and the FDA, and is updated regularly. It is created by eHealthMe based on reports of 401,887 people who have side effects when getting Pfizer BioNTech Covid Vaccine from the CDC and the FDA, and is updated regularly. And of course, most experts agree that if it's been more than five or six months since you got Covid-19 and you haven't been boosted yet, you should do so as soon as you're eligible. People may mistake these symptoms for arthritis. 'Rest is the most important factor of treating SIRVA - you need to give the muscles, tendons and ligaments time to recover as this problem often causes inflammation. Although he was healthy before he received the COVID-19 vaccine, he began having symptoms of RA 4 weeks after his final vaccination. Med Sci Monit. Assessment 4: This will be performed between 181 to 360 days after the onset of symptoms of COVID-19 infection. Even going to a toilet has its risks. and transmitted securely. Smoking, older age, and preexisting joint pain had links to post-COVID-19 arthritis. After adjustment for baseline characteristics, the study found that the hazard of aortic aneurysm increased by 2.24-fold (95% CI=2.02-2.49) during a 30-day risk window following the treatment episode. However, various side effects have been reported following vaccination. Epub 2022 Jun 8. A spokesperson for HRSA confirmed to MedPage Today via email that despite full FDA approval, Pfizer's COVID-19 vaccine (Comirnaty) still remains covered under the CICP and does not yet move to the VICP. Research suggests that overactive bladder and COVID-19 have links. from the American Academy of Orthopaedic Surgeons, Swelling or redness at the site of the injection, Systemic reactions, such as fever, chills, nausea, vomiting, muscle aches, or fatigue. COVID-19 Vaccines and Allergic Reactions You'll always want to stay at your vaccination site for at least 15 minutes after you get the shot (30 minutes if you've had a severe allergic. The patient provided informed consent to publish this case. I'm still discovering new areas of damage -- Richard Quest. Musculoskeletal corticosteroid injections are common procedures which are most often performed in an elective, outpatient setting. The phase IV clinical study analyzes which people get Pfizer BioNTech Covid Vaccine and have Tendonitis. If an MRI shows a complete muscle injury, surgical repair may be required. 8600 Rockville Pike Can the Cornonavirus Affect My Bones and Joints? He or she may also recommend waiting for a period of time after vaccination.Your doctor can answer any questions you may have about the timing of corticosteroid injections and COVID-19 vaccination. Systemic reactions in persons aged 6-23 months, Pfizer BioNTech BNT162b2 COVID-19 vaccine and placebo a Any fever= 38.0C b Mild: decreased interest in eating; moderate: decreased oral intake; severe: refusal to feed; Grade 4: emergency room visit or hospitalization Sex and gender exist on spectrums. The use of the eHealthMe site and its content is at your own risk. All data and statistics are based on publicly available data at the time of publication. 2022 Aug 12;40(34):4964-4971. doi: 10.1016/j.vaccine.2022.06.002. . Note as well that despite the recent full FDA approval for the Pfizer COVID-19 vaccine, any injuries attributed to it at the present time still remain covered under the CICP. Treatment for joint pain is available. Bethesda, MD 20894, Web Policies What are some of the best ways to clear phlegm with COVID-19? Jackson can still do her job as a veterinarian, but it can be painful lifting animals during surgery, for instance. They examined 100 people from Egypt who had recovered from COVID-19 several months prior. Recap. This resource was created to help address concerns you may have about the effect of the COVID-19 vaccine on your musculoskeletal health. However, the report does not confirm that this happened. What is the latest research on the form of cancer Jimmy Carter has? Additionally, the COVID-19 vaccine may cause arthritis-like side effects that can last weeks. Symptoms can vary depending on where the aberrant shot landed, resulting in various manifestations such as bursitis, tendonitis, or adhesive capsulitis (also known as "frozen shoulder"). Both programs are administered by the Health Resources and Services Administration (HRSA). "We might see edema and inflammatory changes of the tissues (fluid, swelling), hematomas (collections of blood) or devitalized tissue (gangrene)," Deshmukh said. Different individuals may respond to medication in different ways. Skin reactions to the COVID vaccine aren't just limited to where you get your jab. Published by Oxford University Press. Content on this website is for information only. Plantar fasciitis and Achilles tendinitis were already top causes of heel and foot pain, and the sequestered pandemic lifestyle many people have adopted has worsened the problem. Normally, taking your shoes off when you get home at the end of the day isn't a big deal. The other injuries to receive compensation were anaphylaxis, shoulder pain, bursitis and one death. Shoulder Pain and Injury after COVID-19 Vaccination. Northwestern University. If you are allergic to polyethylene glycolone of the ingredients used in the COVID-19 vaccinethe CDC advises against being vaccinated. This included injuries to the soft tissues of the shoulder as well as injuries to bone and joint. The site is secure. They reduce inflammationmarked by swelling, redness, and warmththat is controlled by the immune system. For example, Deshmukh said, if a patient has persistent shoulder pain that started after contracting COVID, their primary care provider might order an MRI/ultrasound. COVID arm is a minor annoyance that will disappear within a few days. Of the initial COVID-19 claims, the . A Baylor College of Medicine vaccine expert weighs in on . Cardiovascular health: Insomnia linked to greater risk of heart attack. 713-798-4710. One of those is muscle and joint pain from COVID-19. You can learn more about how we ensure our content is accurate and current by reading our. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. It's also different from typical post-injection soreness, as the pain is more severe and it can impact mobility and function. When that table is developed, those who couldn't establish a "Table" injury have a year to file a request for benefits even if their previous request was denied. pdf files, Reactivation of IgA vasculitis after COVID-19 vaccination, The Lancet Regional Health Southeast Asia, Statement on offensive historical content. Kristina Fiore leads MedPages enterprise & investigative reporting team. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. . Nonsteroidal anti-inflammatory drugs are the first-line treatment when reactive arthritis starts. Other viral infections can do so as well. The COVID-19 vaccine may trigger an RA flare in people who already have the condition, but experts still strongly urge people with the condition to get vaccinated. Read more: Questions and Answers for Patients Regarding Elective Surgery and COVID-19. "Despite the risk of SIRVA, given the notable personal and public health benefits of vaccinations, particularly in light of the coronavirus pandemic, we strongly recommend that patients receive vaccinations," the Wiesel and Keeling paper stated. Symptoms usually begin within a few hours of vaccine administration. Shoulder injury related to vaccine administration (SIRVA) following mRNA COVID-19 vaccination: Report of 2 cases of subacromial-subdeltoid bursitis. Even if the vaccine is inadvertently injected into either of these spaces, studies have shown that it will have no harmful side effects. Clinical Imaging. One of these conditions is rheumatoid arthritis (RA). Yes, COVID-19 can trigger arthritis in some people. Shes been a medical journalist for more than a decade and her work has been recognized by Barlett & Steele, AHCJ, SABEW, and others. Muscle soreness and achy joints are common symptoms among COVID-19 patients. Japan College of Rheumatology 2022. Bookshelf an abnormal one at injection site), Injection site paraesthesia (abnormal skin sensations at injection site), Injection site pruritus (severe itching at injection site), Injection site urticaria (rash of round, red welts on the skin at injection site), Injection site vesicles (fluid- or air-filled cavity or sac at injection site), Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain), Joint range of motion decreased (disease of joint movement), Leukocytosis (increased white blood cells), Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung), Lymphadenitis (inflammation or enlargement of a lymph node), Lymph follicular hypertrophy (an increase in the size of the lymph node follicles), Lymphoedema (localized fluid retention and tissue swelling), Malaise (a feeling of general discomfort or uneasiness), Mastication disorder (disease of chewing food), Maternal exposure during pregnancy (use of substance during pregnancy), Menstrual disorder (disease of menstrual cycle), Menstruation delayed (late menstruation cycle), Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability), Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition), Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation), Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy), Middle ear effusion (fluid in middle ear), Migraine with aura (headache with vision weakness), Mitral valve incompetence (inefficient heart valve), Mobility decreased (ability to move is reduced), Monoplegia (a paralysis of a single limb), Mood swings (an extreme or rapid change in mood), Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness), Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Factors that may contribute include: COVID-19 vaccines can also cause temporary side effects that feel similar to those of arthritis or RA, such as: These effects usually last a few days but can last up to several weeks. https://www.ncbi.nlm.nih.gov/books/NBK499831/, https://www.yourcovidrecovery.nhs.uk/i-think-i-have-long-covid/effects-on-your-body/joint-and-muscle-problems/, https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html, https://www.niams.nih.gov/health-topics/reactive-arthritis, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162104/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831681/, https://www.frontiersin.org/articles/10.3389/fimmu.2022.859926/full. It was such a strange, unfamiliar sensation that I didn't realize what was happening. 2023 eHealthMe.com. There is no evidence that vaccination will interfere with your surgery or recovery. Her primary care doctor referred her to a physical medicine & rehabilitation specialist who, after confirming bursa and joint inflammation on imaging, prescribed steroid and lidocaine injections along with physical therapy. Studies show that these conditions occur no more often in patients who have received vaccination than they do in the overall population. Can the COVID-19 vaccine cause arthritis? The mRNA instructs the bodys cells to manufacture a spike protein that is found on the surface of the COVID- 19 virus. The American Academy of Orthopaedic Surgeons (AAOS) has recently stated that the benefits of the COVID-19 vaccine strongly outweigh the orthopaedic risks. Other potential reactive arthritis symptoms include: According to the National Library of Medicine, if a person still has the infection that led to reactive arthritis, treatment focuses on the infection. Tendonitis is found among people who get Pfizer BioNTech Covid Vaccine, especially for people who are female, 60+ old, and in the first week of getting the vaccine. These can include intra-articular, bursal, tendon . Fatigue (feeling of tiredness): 25 people, 13.89%, Mobility Decreased (ability to move is reduced): 17 people, 9.44%, Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 8.89%, Muscle Aches (muscle pain): 15 people, 8.33%, Hypoaesthesia (reduced sense of touch or sensation): 14 people, 7.78%. Physical therapy helped improve his range of motion to an extent, but his pain lingers. For patients presenting with unremitting shoulder pain and reduced shoulder range of motion after recently receiving a SARS-CoV-2 vaccine, clinicians should consider SIRVA in their differential diagnosis, along with . Opens in a new tab or window, Share on Twitter. Please enable it to take advantage of the complete set of features! These symptoms may last weeks or months. Dr. The benefits usually outweigh the risks, as people with RA are more vulnerable to severe COVID-19. Reports of people experiencing tinnitus, vertigo and other hearing problems after having COVID-19 started emerging earlier in the pandemic. Last medically reviewed on December 11, 2022. However, a 2022 case report notes that some people have developed new or worse symptoms of autoimmune conditions after receiving the COVID-19 vaccine. "We've realized that the COVID virus can trigger the body to attack itself in different ways, which may lead to rheumatological issues that require lifelong management," said corresponding author Dr. Swati Deshmukh. If a person has persistent joint pain after any infection, they should contact a doctor. Radiographs showed calcification of the supraspinatus tendon, and magnetic resonance images showed continuous inflammatory findings from the subdeltoid bursa to the subacromial bursa. Opens in a new tab or window, Visit us on Facebook. The pain associated with Achilles tendonitis typically begins as a mild ache in the back of the leg or above the heel after running or other sports activity. The COVID-19 vaccine is safe and does not cause arthritis in the vast majority of people. Before But for some people, symptoms are more severe, long lasting and even bizarre, including rheumatoid arthritis flares, autoimmune myositis or "COVID toes.". A statement from Johnson & Johnson said that tinnitus was identified as an adverse event in its phase 3 clinical trials of the Covid-19 vaccine but also maintained that it was impossible to. 401,887 people reported to have side effects after getting Pfizer BioNTech Covid Vaccine. The vaccine should slow the spread of COVID-19 around the world. We avoid using tertiary references. However, his Tweets are now being viewed in a dangerous light, mostly by people attempting to promote anti-vaccination theories. READ MORE: Covid pneumonia symptoms: Five . 2021 Nov;50(11):2293-2297. doi: 10.1007/s00256-021-03803-x. Shoulder injury related to vaccine administration, or SIRVA, has been documented long before COVID-19 vaccination, and is most frequently reported after influenza vaccination. Have any problems using the site? This information is provided as an educational service and is not intended to serve as medical advice. Our phase IV clinical studies alone cannot establish cause-effect relationship. Vaccine. All material on this website is protected by copyright. Shoulder injury related to vaccine administration (SIRVA) is an uncommon event, but can occur after vaccination for SARS-CoV-2. Generally, it's characterized as a "constellation of shoulder pain and reduced range of motion that occurs within 48 hours of vaccination and does not resolve within 1 week," according to a. Copyright 1995-2021 by the American Academy of Orthopaedic Surgeons. (2022). Houston, TX - Feb 11, 2021. The first is a type of tendonitis known as De Quervain's tenosynovitis. The puncture point should be chosen with the median point of the deltoid muscle or the anterior-posterior axillary line as landmarks because the more cephalad the puncture position, the greater the chance of causing SIRVA. Both Noren and Jackson said their insurance covers their medical bills, and they both feel relieved that they can still work, but they're frustrated that there's no federal protection for SIRVA related to COVID-19 vaccines. An MRI revealed fluid collecting in his joint, as well as adhesive capsulitis, he said. 2022 Jul 11;28:e937430. 2022;40(18):2546-2550. Like any vaccine, a COVID-19 vaccine may cause pain, swelling, and fever after being administered. While healthcare providers anticipate a sharp increase in reported cases in the coming year given the large volume of COVID vaccinations, Wiesel and Keeling warned that data on the condition are still limited -- they're "virtually absent from the orthopedic literature" -- and that the "current understanding of the diagnostic workup of SIRVA is limited to the medicolegal realm.". Some people recover from long COVID in a few weeks, but others do not recover completely. Stroke in Tamsulosin, how severe and when it was recovered? sharing sensitive information, make sure youre on a federal All rights reserved. Kennedy, MD, chair of physical medicine & rehabilitation at of Vanderbilt University Medical Center in Nashville, told MedPage Today. Views expressed here do not necessarily reflect those of ScienceDaily, its staff, its contributors, or its partners. Three months is a . If you are having a corticosteroid injection for an orthopaedic condition, such as arthritis or carpal tunnel syndrome, your doctor may advise you to wait for a few days after the injection before receiving the COVID-19 vaccine. This applies . Symptoms may include frequent urination and burning pain while urinating. All rights reserved. Clipboard, Search History, and several other advanced features are temporarily unavailable. What is the link between joint swelling and COVID-19? We study millions of patients and 5,000 more each day. There is still a very small chance that you can get COVID-19. SIRVA (Shoulder Injury Related to Vaccine Administration) following mRNA COVID-19 Vaccination: Case discussion and literature review. Yale J Biol Med. While the connection between tinnitus and the Covid vaccine are not yet understood: The British Tinnitus Association has labeled tinnitus a rare side effect of the vaccine. What to know about COVID-19 and arthritis. Many patients who have had the virus have a positive antibody test. It happens when the vaccine is injected not into the muscle, as it should be, but into the bursa space below the muscle. The tinnitus remains after six weeks with no end in sight. The HRSA spokesperson said the CICP covers "eligible serious injuries" -- generally, those that require hospitalization or that lead to significant disability. Resting your body may help to. The authors of the case report suggest that the vaccine may have triggered an inflammatory response that led to the mans symptoms. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Visit our coronavirus hub for the most recent information on the COVID-19 pandemic. The COVID virus triggered rheumatoid arthritis in this patient with prolonged shoulder pain after other covid symptoms resolved. BNT162b2 contains mRNA encoding for the SARS-CoV-2 spike protein encapsulated in lipid nanoparticles, in addition to other components that stabilise the vaccine in the circulation and promote its uptake into cells by endocytosis. pain and swelling in the joints, especially the large joints of the legs, such as the ankles and knees, symptoms that affect only one side of the body, performing strengthening exercises, which prevent muscle wasting. Three COVID-19 vaccines have been approved for emergency use in the USA so far. No studies have found a direct link between the vaccine and arthritis. But during the pandemic, many people's entire workday has been spent at home. Tendonitis Laura Keeling, MD, an orthopedic surgeon at MedStar Georgetown University Hospital in Washington, D.C., told MedPage Today that part of the reason SIRVA remains in the medicolegal realm is that it's "more of a constellation of symptoms and findings" rather than a specific diagnosis. Shoulder injury related to vaccine administration (SIRVA) after COVID-19 vaccination. "It's important for doctors to know what's happening in order to treat correctly.". 04:20. HHS Vulnerability Disclosure, Help KAT and FKT both contributed to direct care of the patient. CNN . Assessment 2: This will be performed between 31 to 90 days after the onset of symptoms of COVID-19 infection. Other Northwestern authors on the paper were Santhoshini Leela Ramani (Northwestern University medical student), Dr. Jonathan Samet (radiology), Dr. Colin Franz (PMR and neurology), Dr. Christine Hsieh (rheumatology), Dr Cuong Nguyen (dermatology) and Dr. Craig Horbinski (pathology). Among them, 180 people (0.04%) have Tendonitis. Other possible symptoms include: Although long COVID is more common in people who have had a severe case of COVID-19, it can happen even in those with a very mild case. Tendonitis in Johnson & Johnson COVID Vaccine, Abortion spontaneous (naturally occurring miscarriage), Acute myocardial infarction (acute heart attack), Acute upper airway obstruction (blockage occurs in the upper airway), Ageusia (loss of taste functions of the tongue), Agitation (state of anxiety or nervous excitement), Alopecia areata (patchy baldness that typically begins with rapid hair loss), Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death), Angioedema (rapid swelling of the dermis), Appendicitis (inflammation of the appendix), Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat), Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires), Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system), Arthritis (form of joint disorder that involves inflammation of one or more joints), Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem), Atelectasis (partial or complete collapse of the lung), Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles), Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue), Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis), Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones), Belching (release of gas from the digestive tract), Blindness transient (sudden loss of vision), Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure), Blood thyroid stimulating hormone decreased, Blood thyroid stimulating hormone increased, Bradycardia (abnormally slow heart action), Breast lump (localized swelling that feels different from the surrounding breast tissue), Bronchitis (inflammation of the mucous membrane in the bronchial tubes), Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle), Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder), Canker sores (painful, open sore in the mouth), Cardiomyopathy (weakening of the heart muscle), Cardio-respiratory arrest (sudden dysfunction of heart and lungs), Cerebral haemorrhage (bleeding within the brain), Cerebral infarction (less blood supply to brain resulting tissue damage), Cerebral thrombosis (blood clot in brain), Chapped lips (cracking, fissuring, and peeling of the skin f lip), Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe), Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving), Concussion (short loss of normal brain function in response to a head injury), Coronary artery occlusion (complete obstruction of blood flow in a coronary artery), Coronary heart disease (narrowing or blockage of the coronary arteries), Crohn's disease (condition that causes inflammation of the gastrointestinal tract), Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis), Dehydration (dryness resulting from the removal of water), Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it), Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens), Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies), Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall), Drooling (drop saliva uncontrollably from the mouth), Dyskinesia (abnormality or impairment of voluntary movement), Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear), Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters), Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat), Ejection fraction decreased (systolic heart failure), Encephalopathy (functioning of the brain is affected by some agent or condition), Euphoric mood (excessively happy but may become angry or irritable), Eyelid ptosis (falling of the upper or lower eyelid), Eyelid twitch (spontaneous and uncontrolled spasms of the muscles), Facial paralysis (loss of function of face muscle), Facial paresis (weakness in facial muscle movement), Fainting (loss of consciousness and postural tone), Feeding disorder (when children refuse to eat certain food groups), Fibromyalgia (a long-term condition which causes pain all over the body), Flank pain (a distressing sensation experienced around the lower back and the upper abdomen), Flatulence (flatus expelled through the anus), Fluid retention (an abnormal accumulation of fluid in the blood), Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin), Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus), Gastrointestinal disorder (functional problems of gastrointestinal tract), Gastrointestinal haemorrhage (bleeding gastrointestinal tract), Gaze palsy (disorders affecting the ability to move both eyes in the same direction), General physical health deterioration (weak health status), Glossodynia (a burning or painful sensation in the tongue), Gout (uric acid crystals building up in the body), Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system), Haematochezia (passage of stools containing blood), Haematoma (collection of blood outside the blood vessels), Hallucinations (sensations that appear real but are created by your mind), Heart palpitations (feelings or sensations that your heart is pounding or racing), Hemiparesis (weakness on one side of the body), Hemiplegia (paralysis of one side of the body), Herpes simplex (herpes simplex is a common viral infection), Hyperacusis (disorder in loudness perception), Hyperhidrosis (abnormally increased sweating), Hyperkalemia (damage to or disease of the kidney), Hyperthyroidism (over activity of the thyroid gland), Hypervolaemia (abnormally increased volume of blood), Hypoaesthesia (reduced sense of touch or sensation), Hypoaesthesia oral (reduced sense of touch or sensation in mouth), Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration), Hypotension (abnormally low blood pressure), Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development), Idiopathic pulmonary fibrosis (chronic lung disease), Incoherent (talking in a confused and unclear way), Incontinence (lack of moderation or self-control), Injection site erythema (redness at injection site), Injection site haemorrhage (bleeding from injection site), Injection site nodule (small swelling or aggregation of cells in the body, esp.

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